The hypothalamus and pituitary gland together serve as the command center of the endocrine system, and the core of the relationship between the endocrine and nervous systems. Together, they regulate virtually every physiological activity in the body.

As mentioned earlier, the nervous and endocrine systems also regulate each other: neurohormones from the hypothalamus direct the release of endocrine hormones, and hormones from the endocrine system regulate nervous system activity.

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